β-Blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women. Despite the common use of this class of medication, data that support its safety are limited. β-Blockers cross the placenta and potentially can cause physiological changes in the fetus.
Which beta blocker is not safe in pregnancy?
Conclusions The authors found that exposure to β-blockers during pregnancy was associated with being born SGA, preterm birth and perinatal mortality. Our findings show that labetalol is not safer than other β-blockers during pregnancy.
Is propranolol contraindicated in pregnancy?
There are no concerns that taking propranolol in pregnancy causes harm. Propranolol belongs to a family of medicines called beta blockers. Studies have not shown that beta blockers cause birth defects, stillbirth or preterm birth.
What is the best beta blocker in pregnancy?
It is concluded that atenolol and labetalol are safe and they are usually effective in the control of the hypertension complicating pregnancy. But labetalol appears to be better able to prevent the appearance of fetal growth retardation.
Who are beta blockers contraindicated?
Traditional contraindications to beta-blockers are peripheral vascular diseases, diabetes mellitus, chronic obstructive pulmonary disease (COPD) and asthma.
Is metoprolol okay while pregnant?
Are there any risks of taking metoprolol in pregnancy? A small number of pregnant women specifically taking metoprolol have been studied, with no concerns raised that its use causes birth defects or preterm birth. Metoprolol belongs to a family of medicines called beta blockers.
Why is atenolol contraindicated in pregnancy?
One study did find that atenolol can directly affect blood flow through the placenta, which might be associated with poor growth of the baby. Can taking atenolol near delivery cause problems for the baby? Atenolol use in late pregnancy may cause the newborn baby to have a slowed heart rate and low blood sugar.