Can I take Zofran while pregnant?

Zofran is approved by the Food and Drug Administration (FDA) for use to fight off nausea related to chemotherapy. It is not currently approved by the FDA for morning sickness. Even so, most studies show that ondansetron is safe to use during the first trimester when most women experience morning sickness.

Will Zofran hurt my unborn baby?

If you are pregnant and have taken ondansetron or Zofran® during pregnancy, I want to reassure you that it likely has not affected your baby. Even if the increased risk for cleft palate or heart defects turns out to be true, the risk to your baby is still very, very small.

Can you take Zofran at 6 weeks pregnant?

A new study published in the New England Journal of Medicine concluded that the popular drug Zofran (used to treat nausea, vomiting and in some cases, hyperemesis gravidarum, in early pregnancy) poses no risk to the developing fetus.

Will Zofran cause miscarriage?

Does taking ondansetron increase the chance for miscarriage? Miscarriage can occur in any pregnancy. One study did not find that miscarriage happened more often for those who reported that they used ondansetron in the first trimester of pregnancy.

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Can I take Zofran in first trimester?

Zofran is approved by the Food and Drug Administration (FDA) for use to fight off nausea related to chemotherapy. It is not currently approved by the FDA for morning sickness. Even so, most studies show that ondansetron is safe to use during the first trimester when most women experience morning sickness.

What can I take for nausea while pregnant?

If your morning sickness symptoms persist, your health care provider may recommend vitamin B-6 supplements (pyridoxine), ginger and over- the-counter options such as doxylamine (Unisom) for management. If you still have symptoms, your health care provider may recommend prescription anti-nausea medications.

Why is Zofran not safe during pregnancy?

One recent meta-analysis of eight studies suggested that exposure to ondansetron in the first trimester could cause a very small increase in the risk of heart defects and orofacial malformations like cleft palate in babies.

When should you not take Zofran?

You should not use Zofran if you are allergic to ondansetron or to similar medicines such as dolasetron (Anzemet), granisetron (Kytril), or palonosetron (Aloxi). Zofran orally disintegrating tablets may contain phenylalanine. Tell your doctor if you have phenylketonuria (PKU).

Does Zofran help with morning sickness?

Ondansetron (Zofran®) is a medicine used to treat nausea and vomiting that may be caused by surgery, chemotherapy, or radiation therapy. Healthcare professionals also prescribe ondansetron during pregnancy to reduce symptoms of nausea and vomiting, also known as “morning sickness.”

Can Zofran cause cleft palate?

Data from the National Birth Defects Prevention Study shows Zofran causes a 237% risk of birth defect cleft palate. Up to 80% of women experience nausea and vomiting during pregnancy, nearly 16% of which take medication to help control these symptoms.

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What class is Zofran for pregnancy?

The FDA has classified Zofran as a “Pregnancy Category B” drug, meaning that it has not been the subject of any well-controlled studies to determine the effects Zofran may have during pregnancy. However, the FDA has approved “Pregnancy Category A” drug called Diclegis to safely treat morning sickness in pregnant women.

How fast does Zofran work?

How quickly does Zofran (ondansetron) work? Zofran (ondansetron) should work pretty quickly. Many people report relief within about 30 minutes and it reaches maximum blood concentrations in about 2 hours. The effects of Zofran (ondansetron) can last anywhere between 8 to 12 hours.

How safe is Zofran?

Zofran may cause headaches, drowsiness, constipation and other mild side effects. In rare cases, the anti-nausea medication can cause erratic heartbeats and high serotonin levels, which may be life-threatening. The drug has also been said to cause birth defects, though research findings are mixed.

When is morning sickness the worst?

Even though it’s called morning sickness, it can last all day and happen any time of day. At least 7 in 10 pregnant women have morning sickness in the first trimester (first 3 months) of pregnancy. It usually starts at about 6 weeks of pregnancy and is at its worst at about 9 weeks.